Konstantinou Christothea, Xanthopoulos Andrew, Tsaras Konstantinos, Skoularigis John, Triposkiadis Filippos, Papagiannis Dimitrios
Public Health & Vaccines Laboratory, Faculty of Nursing, University of Thessaly, Larissa, GRC.
Department of Cardiology, University Hospital of Larissa, Larissa, GRC.
Cureus. 2022 Sep 8;14(9):e28936. doi: 10.7759/cureus.28936. eCollection 2022 Sep.
Background Human papillomavirus (HPV) has been associated with the development of several cancers and cardiovascular diseases in females. Nevertheless, there is still poor data on vaccination coverage against HPV in several countries, including Cyprus. The main target of the present research was to assess the vaccination status of female students in Cyprus. Methodology An online survey was conducted via a cloud-based short questionnaire on Google Forms. Students with a known email address were initially invited via email to complete the survey. The questionnaire was distributed to 340 students, aged 18-49 years old, who lived in Cyprus (60% response rate). Results The total vaccination coverage was 38.1%. The mean age of participants was 23.5 (±6.5) years. The major reason for non-vaccination was the belief that participants were not at risk of serious illness from HPV infection (22%), followed by the reported lack of time to get vaccinated (16%) and inertia (13%). The students who had information about the safety of HPV vaccines from electronic sources of information (television, websites, and blogs) had lower vaccination coverage compared to those who had received information from alternative sources (primary health centers, family doctors, or obstetricians) (relative risk (RR) = 1.923, 95% confidence interval (CI) = 0.9669-3.825; p = 0.033). No significant differences in vaccination rates between participants who were coming from schools of health sciences versus those from financial schools (RR = 1.082, 95% CI = 0.7574-1.544; p = 0.3348) were observed. Conclusions Public health policy interventions and education on HPV vaccines are effective ways to improve the awareness and acceptance rate of HPV vaccination among female students and improve the HPV vaccination coverage level in Cyprus.
背景 人乳头瘤病毒（HPV）与女性多种癌症和心血管疾病的发生有关。然而，包括塞浦路斯在内的几个国家关于HPV疫苗接种覆盖率的数据仍然匮乏。本研究的主要目的是评估塞浦路斯女学生的疫苗接种状况。方法 通过谷歌表单上基于云的简短问卷进行在线调查。最初通过电子邮件邀请有已知电子邮件地址的学生完成调查。问卷分发给了340名年龄在18 - 49岁、居住在塞浦路斯的学生（回复率为60%）。结果 总疫苗接种覆盖率为38.1%。参与者的平均年龄为23.5（±6.5）岁。未接种疫苗的主要原因是认为参与者没有感染HPV而患重病的风险（22%），其次是报告称没有时间接种疫苗（16%）和惰性（13%）。与从其他来源（初级卫生保健中心、家庭医生或产科医生）获得信息的学生相比，从电子信息来源（电视、网站和博客）了解HPV疫苗安全性的学生疫苗接种覆盖率较低（相对风险（RR）= 1.923，95%置信区间（CI）= 0.9669 - 3.825；p = 0.033）。来自健康科学学院的参与者与来自金融学院的参与者之间的疫苗接种率没有显著差异（RR = 1.082，95% CI = 0.7574 - 1.544；p = 0.3348）。结论 公共卫生政策干预和HPV疫苗教育是提高女学生对HPV疫苗接种的认识和接受率以及提高塞浦路斯HPV疫苗接种覆盖率的有效途径。
