Department of Cerebrovascular Neurology, Flinders Medical Centre, Bedford Drive, Bedford Park, S.A. 5042, Australia.
Cerebrovasc Dis. 2009;28(6):618-22. doi: 10.1159/000251173. Epub 2009 Oct 22.
To describe the ophthalmology findings in patients with cerebral amyloid angiopathy (CAA).
Data source and subjects: 7 consecutive patients admitted to a tertiary stroke unit with CAA-related hemorrhage, confirmed on magnetic resonance brain imaging gradient echo sequences by 2 independent neuroradiologists.
case series. Measurements and data analysis: fundus colored photographs and fundus fluorescein angiography.
All patients showed bilateral multiple dot and blot hemorrhages as well as multiple microaneurysms on fundus fluorescein angiography.
Microaneurysms and dot and blot hemorrhages funduscopically mirror the histopathology of CAA. This case series is the first to describe retinal vessel changes in CAA and, if confirmed in larger population studies, has the potential to provide insights into the natural history of CAA.
描述脑淀粉样血管病（CAA）患者的眼科表现。
资料来源和对象：连续 7 例因 CAA 相关性出血而入住三级卒中病房的患者，经 2 位独立的神经放射科医生在磁共振脑成像梯度回波序列上证实。
病例系列。
眼底彩色照片和眼底荧光素血管造影。
所有患者眼底荧光素血管造影均显示双侧多发性点、片状出血和多发微动脉瘤。
微动脉瘤和眼底的点、片状出血反映了 CAA 的组织病理学特征。本病例系列首次描述了 CAA 的视网膜血管变化，如果在更大的人群研究中得到证实，有可能深入了解 CAA 的自然病程。
