Constantinescu Monica B, Chan Jessica B, Cassarino David S
Department of Pathology and Laboratory Medicine, University of California Los Angeles, USA.
Am J Dermatopathol. 2010 Apr;32(2):171-4. doi: 10.1097/DAD.0b013e3181aec131.
Chondroid syringoma (CS) is a relatively rare cutaneous mixed tumor arising from sweat glands. It usually presents in the head and neck area as an asymptomatic, slow-growing, firm, circumscribed, lobulated nodule within the dermis or subcutaneous fat. CSs share morphologic similarities with their salivary gland counterparts, pleomorphic adenomas (benign mixed tumors). Although the presence of tyrosine-rich crystalloids in mixed tumors of the salivary gland is well recognized, to our knowledge, this finding has not been previously described in mixed tumors of the skin. We report a case of tyrosine crystalline structures in a CS and review the pertinent literature.
软骨样汗腺螺旋瘤（CS）是一种相对罕见的起源于汗腺的皮肤混合瘤。它通常出现在头颈部，表现为真皮或皮下脂肪内无症状、生长缓慢、质地坚硬、边界清晰、分叶状的结节。CS与其唾液腺对应物多形性腺瘤（良性混合瘤）在形态上有相似之处。虽然在唾液腺混合瘤中富含酪氨酸的晶体的存在已得到充分认识，但据我们所知，这一发现此前尚未在皮肤混合瘤中被描述过。我们报告了一例CS中酪氨酸晶体结构的病例，并回顾了相关文献。
