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[药物性神经增强的选择、局限与伦理]

[Options, limits and ethics of pharmacological neuroenhancement].

作者信息

Normann C, Boldt J, Maio G, Berger M

机构信息

Abteilung Psychiatrie und Psychotherapie, Universitätsklinikum, Hauptstrasse 5, 79104 Freiburg.

出版信息

Nervenarzt. 2010 Jan;81(1):66-74. doi: 10.1007/s00115-009-2858-2.

Abstract

Pharmacological neuroenhancement is an attempt to increase cognitive performance in healthy humans. Learning and memory, attention and vigilance or mood and social interaction are targeted by a modulation of brain plasticity. Firstly, an analysis of the current state of research shows that, until now, clinical trials of neuroenhancing drugs have demonstrated only limited efficacy and long-term side effects remain largely unexplored. Secondly, we argue that, from an ethical perspective, neuroenhancement differs from socially mediated methods of learning. Pharmacological neuroenhancement is based on notions of efficacy and control that threaten to undermine other important aspects of mental capacities.

摘要

药理学神经增强是指试图提高健康人的认知能力。通过调节大脑可塑性来针对学习与记忆、注意力与警觉性或情绪与社交互动。首先,对当前研究现状的分析表明,到目前为止,神经增强药物的临床试验仅显示出有限的疗效,长期副作用在很大程度上仍未得到探索。其次,我们认为,从伦理角度来看,神经增强与社会介导的学习方法不同。药理学神经增强基于功效和控制的概念,这有可能破坏心理能力的其他重要方面。

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