Second Surgical Department, Regina Elena Cancer Institute, Rome, Italy.
World J Surg Oncol. 2009 Oct 23;7:78. doi: 10.1186/1477-7819-7-78.
Liposarcoma is one of the most common soft tissue sarcoma of adult life, usually occurring in the retroperitoneum and the extremities. Primary liposarcoma of the colon is very rare. The optimal treatment has not been established due to the small number of cases reported. We report a case of primary liposarcoma of the colon presenting as a massive intraluminal lesion.
A 79-year-old woman presented with abdominal pain, progressive constipation and weight loss. A CT scan and a colonoscopy revealed an intraluminal mass in the transverse colon and multiple intraperitoneal lesions. The patient underwent surgical resection of the lesions. Pathologic examination was consistent with pleomorphic liposarcoma of the colon.
Although no guidelines are available for the management of liposarcoma of the colon, surgical resection should be performed when feasible. Our patient's overall survival was satisfactory in spite of the multiple negative prognostic factors.
脂肪肉瘤是成人中最常见的软组织肉瘤之一,通常发生在后腹膜和四肢。结肠原发性脂肪肉瘤非常罕见。由于报道的病例数量较少,尚未确定最佳治疗方法。我们报告了一例以巨大腔内病变为表现的结肠原发性脂肪肉瘤。
一名 79 岁女性因腹痛、进行性便秘和体重减轻就诊。CT 扫描和结肠镜检查显示横结肠腔内肿块和多个腹腔内病变。患者接受了病变的手术切除。病理检查符合结肠多形性脂肪肉瘤。
虽然目前尚无结肠脂肪肉瘤的治疗指南,但在可行的情况下应进行手术切除。尽管存在多个预后不良因素,我们患者的总体生存情况仍令人满意。