微管长度控制：一项团队运动？
Microtubule length control, a team sport?
作者信息
Wordeman Linda, Stumpff Jason
机构信息
Department of Physiology and Biophysics. University of Washington School of Medicine. Seattle, WA 98195, USA.
出版信息
Dev Cell. 2009 Oct;17(4):437-8. doi: 10.1016/j.devcel.2009.10.002.
Abstract
Kinesin-8 family members function in microtubule length control and exhibit highly processive plus-end directed motility in conjunction with microtubule dissassembly activity. In a recent issue of Cell, Varga and colleagues describe how these two activities may be used to simultaneously measure and adjust the length of cellular microtubules.
摘要
驱动蛋白-8家族成员在微管长度控制中发挥作用，并在微管拆卸活性的协同作用下表现出高度持续的正端定向运动。在最近一期的《细胞》杂志上，瓦尔加及其同事描述了如何利用这两种活性同时测量和调整细胞微管的长度。
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Force- and kinesin-8-dependent effects in the spatial regulation of fission yeast microtubule dynamics.裂殖酵母微管动力学空间调控中力和驱动蛋白8依赖性效应
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Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movement.裂殖酵母的驱动蛋白-8：一种异源二聚体、正端定向的分子马达，可将微管解聚与货物运输耦合起来。
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