Rehabilitation Center De Trappenberg, 1272 EX Huizen, The Netherlands.
Neuromuscul Disord. 2009 Nov;19(11):754-8. doi: 10.1016/j.nmd.2009.07.009.
Patients with Duchenne muscular dystrophy (DMD) frequently report lower urinary tract symptoms at the outpatient rehabilitation clinic. The purpose of this study was to determine the prevalence of lower urinary tract symptoms in the Dutch male DMD population and their effect on quality of life. A postal questionnaire was sent to members of Dutch DMD patient organisations. 199 male patients with confirmed DMD and over the age of 3years were included. 170/199 (85%) patients reported one or more lower urinary tract symptoms. Generally, post micturition dribble, straining and feeling of incomplete emptying were most frequently mentioned. 42% of patients (range 18-76%) experienced the symptoms as a problem. In 49/170 (29%) patients, it reduced quality of life. In conclusion, lower urinary tract symptoms in DMD patients are under reported and under diagnosed. However, the vast majority of male DMD patients with symptoms experience them as a problem, often reducing quality of life.
患有杜氏肌营养不良症（DMD）的患者在门诊康复诊所经常报告下尿路症状。本研究的目的是确定荷兰男性 DMD 人群中下尿路症状的患病率及其对生活质量的影响。我们向荷兰 DMD 患者组织的成员发送了一份邮寄问卷。共纳入了 199 名确诊 DMD 且年龄超过 3 岁的男性患者。170/199（85%）名患者报告了一种或多种下尿路症状。一般来说，排尿后滴沥、用力和排空不完全的感觉是最常提到的症状。42%的患者（18-76%的范围）认为这些症状是个问题。在 170 名患者中有 49 名（29%）的患者认为这些症状降低了生活质量。总之，DMD 患者的下尿路症状报告不足且诊断不足。然而，大多数有症状的男性 DMD 患者都认为这些症状是个问题，常常降低了生活质量。
