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Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide.

作者信息

Fyfe Paul K, Rao Vincenzo A, Zemla Aleksandra, Cameron Scott, Hunter William N

机构信息

Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.

出版信息

Angew Chem Int Ed Engl. 2009;48(48):9176-9. doi: 10.1002/anie.200903407.

DOI:10.1002/anie.200903407
PMID:19859929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3465764/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/ca60694e21c6/ukmss-50045-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/391f63300309/ukmss-50045-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/dc98dc2615d2/ukmss-50045-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/ca60694e21c6/ukmss-50045-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/391f63300309/ukmss-50045-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/dc98dc2615d2/ukmss-50045-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c6/3465764/ca60694e21c6/ukmss-50045-f0003.jpg

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FEBS J. 2008 Feb;275(4):753-62. doi: 10.1111/j.1742-4658.2007.06241.x. Epub 2008 Jan 14.
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Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms.
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