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包括急性 COPD 加重行动计划在内的自我管理教育计划。

A self-management education program including an action plan for acute COPD exacerbations.

机构信息

Respiratory Epidemiology and Clinical Research Unit, Montréal Chest Institute of the McGill University Health Centre, Montréal, Québec, Canada.

出版信息

COPD. 2009 Oct;6(5):352-8. doi: 10.1080/15412550903150252.

Abstract

Exacerbations are an important cause of morbidity and mortality in COPD. We assessed treatment initiation and health care use at exacerbation in patients receiving a self-management education program including an action plan. COPD patients were randomly assigned to usual care or to a comprehensive self-management program "Living Well with COPD" including a written action plan and case manager support, and were followed-up for 12 months. Patients in the usual care were managed by their respective practitioners. Patients in the self-management program received, as part of a written action plan, a prescription of antibiotics and prednisone for self-initiation in case of aggravation of 2 or more symptoms (dyspnea, sputum volume, sputum purulence) for at least 24 hours, and they had the support of a case-manager for reinforcement and monthly telephone follow-ups. At 12 months, 166 patients presented with at least one exacerbation. Exacerbations (606) were confirmed by aggravation of at least one symptom; 403 (67.6%) presented 2 or more. Antibiotics were used in 61.6% of exacerbations and prednisone in 47.9%. In exacerbations presenting aggravation of 2 or more symptoms, antibiotics and prednisone were used together more often in the action plan than in the usual care group (54.4% vs. 34.8%, p < 0.001). In the action plan, compared to the usual care group, 17.2% vs. 36.3% exacerbations resulted in a hospitalization (p < 0.001). Self-management with the successful use of an action plan for acute exacerbation of COPD holds promise for reducing health care use.

摘要

加重是 COPD 患者发病率和死亡率的重要原因。我们评估了接受自我管理教育计划(包括行动计划)的患者在加重时的治疗启动和医疗保健使用情况。将 COPD 患者随机分配到常规护理或综合自我管理计划“与 COPD 一起生活”中,包括书面行动计划和病例经理支持,并随访 12 个月。常规护理组的患者由各自的医生进行管理。自我管理计划组的患者作为书面行动计划的一部分,如果出现 2 个或更多症状(呼吸困难、痰量、痰脓性)加重至少 24 小时,他们会自行启动抗生素和泼尼松治疗,并得到病例经理的支持进行强化治疗和每月电话随访。在 12 个月时,有 166 名患者出现至少一次加重。加重(606 次)是通过至少一个症状的加重来确认的;403 次(67.6%)出现 2 次或更多次。在 61.6%的加重中使用了抗生素,在 47.9%的加重中使用了泼尼松。在出现 2 个或更多症状加重的加重中,行动计划中抗生素和泼尼松联合使用的比例高于常规护理组(54.4%比 34.8%,p<0.001)。在行动计划中,与常规护理组相比,17.2%的加重导致住院治疗,而常规护理组为 36.3%(p<0.001)。对于 COPD 急性加重的自我管理,成功使用行动计划有望减少医疗保健的使用。

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