IV 型肺炎球菌的特异性和非特异性多糖。
SPECIFIC AND NON-SPECIFIC POLYSACCHARIDES OF TYPE IV PNEUMOCOCCUS.
机构信息
Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.
出版信息
J Exp Med. 1931 Apr 30;53(5):625-39. doi: 10.1084/jem.53.5.625.
Abstract
- Three nitrogen-containing polysaccharides have been isolated from autolyzed cultures of Type IV pneumococcus: (1) a type-specific carbohydrate differing markedly from those of Type I, II, and III pneumococcus, and representing a type of substance hitherto not observed among specific polysaccharides, (2) a chemically similar carbohydrate without specific function, and (3) the "C" substance, or species-specific polysaccharide of Tillett, Goebel, and Avery. 2. The chemical differences between the specific polysaccharides of Pneumococcus are discussed, and the relationship of the new examples to chitin is pointed out and its bearing indicated on the unsettled controversy as to whether or not chitin occurs in bacteria. 3. The data of Tillett, Goebel, and Avery on the "C" substance have been extended.
摘要
从 IV 型肺炎球菌自溶培养物中分离出三种含氮多糖：(1) 一种与 I、II 和 III 型肺炎球菌的多糖明显不同的特异性多糖，代表了一种迄今在特异性多糖中未观察到的物质类型；(2) 一种化学性质相似但无特定功能的多糖；(3) 是蒂尔莱特、戈贝尔和艾弗里的“C”物质，或种特异性多糖。
讨论了肺炎球菌特异性多糖之间的化学差异，并指出了新实例与几丁质的关系，并就几丁质是否存在于细菌中这一悬而未决的争议表明了其意义。
对蒂莱特、戈贝尔和艾弗里关于“C”物质的数据进行了扩展。
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