脑膜炎奈瑟菌、炭疽芽孢杆菌、变形杆菌、枯草芽孢杆菌和肠杆菌的多糖的血清学研究。
A SEROLOGICAL STUDY OF THE POLYSACCHARIDES OF MENINGOCOCCUS, B. ANTHRACIS, B. PROTEUS, B. SUBTILIS AND B. MESENTERICUS.
机构信息
Mulford Biological Laboratories, Sharp and Dohme, Glenolden, Pennsylvania.
出版信息
J Exp Med. 1931 Oct 31;54(5):725-32. doi: 10.1084/jem.54.5.725.
Abstract
- The meningococcus polysaccharide reacts with a broad precipitable carbohydrate antibody in common with those of B. anthracis, B. subtilis, B. proteus and B. mesentericus. 2. The anthrax and proteus polysaccharides are specific in the higher dilutions of serum. 3. Antianthrax serum contains two different polysaccharide precipitable antibodies, one specific and the other non-specific. 4. Agglutinins have no relation to the carbohydrate precipitable substance, specific or non-specific. 5. An immunological method is given for the study of the probable chemical relation or similarity of polysaccharides of different bacteria similar to that given by Heidelberger, Goebel and Avery from a strain of Friedländer bacillus and Pneumococcus Type II.
摘要
脑膜炎球菌多糖与炭疽芽胞杆菌、枯草芽胞杆菌、变形杆菌和肠杆菌的广泛可沉淀的碳水化合物抗体发生反应。
在较高稀释度的血清中，炭疽多糖和变形多糖具有特异性。
抗炭疽血清含有两种不同的多糖可沉淀抗体，一种是特异性的，另一种是非特异性的。
凝集素与碳水化合物可沉淀物质、特异性或非特异性无关。
从弗氏流感杆菌和 II 型肺炎球菌菌株，希德勒berger、戈尔贝尔和艾弗里给出了一种免疫方法，用于研究不同细菌的多糖之间可能的化学关系或相似性。
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