不同年龄段人群血清中针对人类流感病毒的中和抗体发生率。
THE INCIDENCE OF NEUTRALIZING ANTIBODIES FOR HUMAN INFLUENZA VIRUS IN THE SERUM OF HUMAN INDIVIDUALS OF DIFFERENT AGES.
机构信息
Hospital of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1936 Apr 30;63(5):655-68. doi: 10.1084/jem.63.5.655.
Abstract
The results of mouse protection tests with 136 human sera and a strain of human influenza virus are described. After the 1st year of life, the sera of approximately half the individuals tested contained sufficient antibody to furnish complete protection to mice. A much higher percentage of the sera obtained from individuals recently convalescent from influenza exerted a completely protective effect. On the other hand, certain sera protected only partially under the conditions of the tests. The results have been compared with those obtained by Shope in tests done with the same sera against swine influenza virus. The possible epidemiological significance of the results is discussed.
摘要
本文描述了用 136 个人血清和一株人流感病毒进行的小鼠保护试验结果。在出生后的第一年，大约一半被测试个体的血清中含有足够的抗体，可为小鼠提供完全保护。最近从流感康复的个体获得的血清中，有更高比例的血清能产生完全的保护作用。另一方面，某些血清在试验条件下只能部分保护。这些结果与 Shope 用相同血清针对猪流感病毒进行的试验结果进行了比较。讨论了这些结果在流行病学方面的可能意义。
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J Exp Med. 1936 Apr 30;63(5):669-84. doi: 10.1084/jem.63.5.669.
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