引起兔乳头瘤的病毒的血清学反应：Ⅱ.携带各种上皮肿瘤动物的血液试验。
SEROLOGICAL REACTIONS WITH A VIRUS CAUSING RABBIT PAPILLOMAS WHICH BECOME CANCEROUS : II. TESTS OF THE BLOOD OF ANIMALS CARRYING VARIOUS EPITHELIAL TUMORS.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1936 Jun 30;64(1):79-96. doi: 10.1084/jem.64.1.79.
Abstract
The serum of a rabbit with large cancers resulting from the transplantation of a squamous cell carcinoma that had arisen from a virusinduced papilloma, possessed the power to neutralize the virus, and so too in less degree did that of an animal of the same transplantation series in which a small nodule had developed. The sera of rabbits carrying tar papillomas or the Brown-Pearce carcinoma proved wholly devoid of effect on the virus. The implantation of Brown-Pearce tumor material mixed with virus did not lead to an enduring establishment of the latter in the resulting growths, nor to any immediate changes in their morphological character. The significance of the facts is discussed.
摘要
从病毒诱导的乳头瘤中发生的鳞癌移植而产生的大肿瘤的兔子血清，具有中和病毒的能力，而在具有小结节的同一移植系列的动物中，其血清的中和能力也较低。携带焦油乳头瘤或 Brown-Pearce 癌的兔子的血清对病毒完全没有效果。将 Brown-Pearce 肿瘤材料与病毒混合植入，不会导致后者在产生的生长物中持久存在，也不会导致其形态特征的任何立即变化。讨论了这些事实的意义。
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