Lilly Laboratories for Clinical Research, Indianapolis City Hospital, and the Lilly Research Laboratories, Indianapolis.
J Exp Med. 1936 Aug 31;64(3):333-8. doi: 10.1084/jem.64.3.333.
The inhibiting action of pancreatic tissue was found to be associated with the unsaturated fatty acid fraction. As small an amount of fatty acid as 0.1 mg. inhibited the chicken sarcoma agent contained in 0.2 cc. of a 1:60 aqueous extract of Chicken Tumor I. The unsaturated fatty acid had an acid number and an iodine number similar to those for oleic acid. Commercial oleic acid also was found to inhibit the growth of the chicken sarcoma in comparable quantities.
人们发现胰腺组织的抑制作用与不饱和脂肪酸部分有关。小到 0.1 毫克的脂肪酸就能抑制每 0.2 毫升鸡肿瘤 I 水提取物中含有的鸡肉瘤剂,而 1:60 稀释的鸡肿瘤 I 水提取物中只含有 0.2 毫升。这种不饱和脂肪酸的酸值和碘值与油酸相似。人们还发现,商业油酸在类似的数量下也能抑制鸡肉瘤的生长。