The Research Laboratory of the California State Department of Public Health, Berkeley.
J Exp Med. 1941 Apr 30;73(5):641-54. doi: 10.1084/jem.73.5.641.
From the lungs of two fatal cases and from the sputum of two non-fatal cases of atypical bronchopneumonia, a psittacosis-like virus was isolated by direct intranasal inoculation of mice. Intraperitoneal injection of the same human material into mice gave negative results. The virus has a relatively high virulence for mice by intranasal or intra-cerebral inoculation, but does not kill after intraperitoneal inoculation. Its virulence for Java ricebirds is low and it fails to produce a carrier state in mice and birds. Two cases showed an increase in complement-fixing antibodies to the new virus and to psittacosis. The virus is antigenically related to the viruses of meningopneumonitis and psittacosis by complement fixation and by active immunity tests in mice.
从两例非典型性支气管肺炎的死亡病例肺部和两例非典型性支气管肺炎的痰中，通过直接鼻腔接种小鼠，分离出鹦鹉热样病毒。将相同的人体材料腹腔内注射入小鼠，结果为阴性。通过鼻腔内或脑内接种，该病毒对小鼠具有相对较高的毒力，但腹腔内接种后不会致死。其对 Java 稻谷鸟的毒力较低，不能在小鼠和鸟类中产生带菌状态。两例患者均显示补体结合抗体对新型病毒和鹦鹉热的增加。该病毒通过补体结合和小鼠主动免疫试验与脑膜炎肺炎和鹦鹉热病毒具有抗原相关性。
