通过 1,3-二硫醇对丙炔基羰基化合物的双共轭加成合成β-羰基硅基-1,3-二硫杂环戊烷的改进方法。
Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.
机构信息
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA.
出版信息
J Org Chem. 2009 Dec 4;74(23):9206-9. doi: 10.1021/jo901950e.
Abstract
Base-mediated double conjugate addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for an efficient and scalable synthesis of beta-carbonyl silyl-1,3-dithianes.
摘要
碱基介导的 1,3-丙二硫醇对各种硅基丙炔醛和酮的双重共轭加成反应，为高效、规模化合成β-羰基硅基-1,3-二硫杂环戊烷提供了可能。
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Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.通过 1,3-二硫醇对丙炔基羰基化合物的双共轭加成合成β-羰基硅基-1,3-二硫杂环戊烷的改进方法。
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