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通气重症监护患者压疮的发生率及危险因素。

Pressure ulcer incidence and risk factors in ventilated intensive care patients.

机构信息

Intensive Care Unit, Hospital General (University Hospital Virgen de las Nieves), Granada, Spain.

出版信息

J Crit Care. 2010 Sep;25(3):469-76. doi: 10.1016/j.jcrc.2009.09.002. Epub 2009 Oct 30.

Abstract

PURPOSE

The aim of this study was to determine the incidence of pressure ulcers (PUs) in ventilated patients in all intensive care units (ICUs) in Granada (Spain) and identify risk factors for their development.

MATERIALS AND METHODS

A prospective cohort study in 9 medical-surgical ICUs was conducted. Two hundred ninety-nine patients with more than 24 hours on mechanical ventilation (MV) were enrolled during 2 periods in a 5-month study. Pressure ulcers of patients were measured according to the European Pressure Ulcer Advisory Panel.

RESULTS

Of the 299 patients initially enrolled, 47 (16%) developed PUs of at least grade II severity. The incidence density of PUs was 13.4 cases per 1000 patient-days of ICU stay and 19.6 cases per 1000 patient-days on MV. Logistic regression identified first-day respiratory sequential organ failure assessment (odds ratio [OR], 1.56; 95% confidence interval [CI], 1.026-2.360; P = .037), fourth-day cardiovascular sequential organ failure assessment (OR, 1.33; 95% CI, 1.066-1.664; P = .012), age (OR, 1.042; 95% CI, 1.013-1.072; P = .004), winter period (OR, 4.60; 95% CI, 1.99-10.59; P < .001), and length of MV before PUs (OR, 1.042; 95% CI, 1.005-1.080; P = .024) as significant independent predictors of PU development.

CONCLUSIONS

Among other factors previously known in ventilated patients, duration of MV and winter period were identified as risk factors for PUs.

摘要

目的

本研究旨在确定西班牙格拉纳达所有重症监护病房(ICU)中接受机械通气(MV)治疗的患者中压疮(PU)的发生率,并确定其发生的危险因素。

材料和方法

对 9 个内科-外科 ICU 进行了前瞻性队列研究。在为期 5 个月的 2 个阶段研究中,纳入了 299 例 MV 时间超过 24 小时的患者。根据欧洲压疮咨询小组(EPUAP)对患者的压疮进行测量。

结果

最初纳入的 299 例患者中,47 例(16%)至少发展为 II 级严重程度的 PUs。ICU 住院患者的 PU 发生率密度为每 1000 患者日 13.4 例,MV 患者为每 1000 患者日 19.6 例。Logistic 回归分析确定了第 1 天的呼吸序贯器官衰竭评估(OR,1.56;95%置信区间 [CI],1.026-2.360;P =.037)、第 4 天的心血管序贯器官衰竭评估(OR,1.33;95% CI,1.066-1.664;P =.012)、年龄(OR,1.042;95% CI,1.013-1.072;P =.004)、冬季(OR,4.60;95% CI,1.99-10.59;P <.001)和发生 PU 前 MV 时间(OR,1.042;95% CI,1.005-1.080;P =.024)是 PU 发生的显著独立预测因素。

结论

除了先前在接受 MV 治疗的患者中已知的其他因素外,MV 持续时间和冬季被确定为 PU 的危险因素。

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