Leggett R W, Williams L R
Metabolism and Dosimetry Research Group, Oak Ridge National Laboratory, TN 37831-6383.
Health Phys. 1991 Feb;60(2):139-54. doi: 10.1097/00004032-199102000-00001.
Estimates of regional blood volumes (BVs) in man are needed for the dosimetry of radionuclides that decay in the circulation to a significant extent. The tabulation of regional BVs in Publication No. 23 of the International Commission on Radiological Protection (ICRP Reference Man document) may be the best available for dosimetric applications but is not consistent with current information for some organs and does not address some important blood pools. The purpose of this paper is to suggest an improved set of reference values for regional BVs in adult humans. The total blood volume (TBV) is viewed as comprising 22 separate pools, including several pools not addressed in the ICRP Reference Man document. Values suggested here for brain, liver, skin, active marrow, inactive marrow, and bone differ by at least a factor of two from those given for ICRP Reference Man.
对于在循环中大量衰变的放射性核素进行剂量测定，需要估算人体各区域的血容量（BV）。国际放射防护委员会第23号出版物（ICRP参考人文件）中的区域血容量列表可能是剂量测定应用中现有最佳的，但对于某些器官而言，它与当前信息不一致，并且未涉及一些重要的血池。本文的目的是提出一套改进的成人体区域血容量参考值。总血容量（TBV）被视为由22个独立的血池组成，包括ICRP参考人文件中未涉及的几个血池。此处建议的脑、肝、皮肤、活跃骨髓、非活跃骨髓和骨骼的血容量值与ICRP参考人中给出的值相比，至少相差两倍。
