用从绵羊分离出并与牛腺病毒2型相关的腺病毒对犊牛进行实验性感染。I. 临床和病毒学研究。

Experimental infection of calves with an adenovirus isolated from sheep and related to bovine Adenovirus type 2 I. Clinical and virological studies.

作者信息

Belák S, Pálfi V, Szekeres T, Tury E

出版信息

Zentralbl Veterinarmed B. 1977 Aug;24(7):542-7. doi: 10.1111/j.1439-0450.1977.tb01023.x.

DOI:10.1111/j.1439-0450.1977.tb01023.x

PMID:199002

Abstract

Colostrum deprived calves were experimentally infected with an adenovirus isolated from sheep and related to bovine adenovirus type 2. The calves showed respiratory symptoms and mild diarrhoea from the third day after infection. Laboratory tests revealed the development of leucopenia, lymphopenia, a drop of the pH of the urine and the appearance of pathological changes in the urine. The animals shed the virus in their nasal discharge, faeces and urine. Comparing the clinical and virological findings with the previous experimental infection of lambs it is concluded, that this type of adenovirus is similarly pathogenic for the two ruminant species.

摘要

初乳缺乏的犊牛通过实验感染了一种从绵羊分离出的、与牛腺病毒2型相关的腺病毒。犊牛在感染后第三天出现呼吸道症状和轻度腹泻。实验室检测显示出现白细胞减少、淋巴细胞减少、尿液pH值下降以及尿液中出现病理变化。动物通过鼻分泌物、粪便和尿液排出病毒。将临床和病毒学结果与之前羔羊的实验感染进行比较后得出结论，这种腺病毒对这两种反刍动物具有相似的致病性。