Lehmkuhl H D, Cutlip R C
Am J Vet Res. 1984 Feb;45(2):260-2.
Twelve 1-week-old colostrum-deprived lambs that were inoculated with ovine adenovirus isolate RTS-151 developed a mild febrile response between postinoculation days (PID) 4 and 10. They were inactive and some had serous nasal discharges; their respiratory rates and efforts were increased. Virus was isolated from nasal secretions from PID 2 to PID 8. Virus also was isolated from tracheal fluid and lung tissue of most lambs at necropsy (between PID 2 and 12), but not from liver, kidney, small intestine, and feces, indicating that the infection was confined to the respiratory tract. Four control lambs remained healthy and neither virus nor serum antibody was detected.
给12只1周龄初乳缺乏的羔羊接种绵羊腺病毒分离株RTS - 151后，在接种后天数（PID）4至10之间出现了轻微的发热反应。它们活动减少，一些有浆液性鼻分泌物；呼吸频率和努力程度增加。在PID 2至PID 8期间从鼻分泌物中分离出病毒。在尸检时（PID 2至12之间），大多数羔羊的气管液和肺组织中也分离出病毒，但在肝脏、肾脏、小肠和粪便中未分离出，表明感染局限于呼吸道。4只对照羔羊保持健康，未检测到病毒和血清抗体。
