一种用于检测嗜肺军团菌血清型5抗体的快速微量凝集技术。

A rapid micro-agglutination technique for the detection of antibody to Legionella pneumophila serogroup 5.

作者信息

Constantine C E, Wreghitt T G

机构信息

Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge.

出版信息

J Med Microbiol. 1991 Jan;34(1):29-31. doi: 10.1099/00222615-34-1-29.

DOI:10.1099/00222615-34-1-29

PMID:1990135

Abstract

A rapid micro-agglutination test (RMAT) for the detection of antibody to Legionella pneumophila serogroup 5 is described. It was found to be both sensitive and specific when compared with the indirect immunofluorescence test. Evaluation of 89 paired sera from patients with respiratory symptoms showed that the incidence of L. pneumophila serogroup 5 respiratory infection in East Anglia is low: only one case was found in this study. The RMAT would be easy to perform as a screening test in a routine serological laboratory.

摘要

本文描述了一种用于检测嗜肺军团菌血清群5抗体的快速微量凝集试验（RMAT）。与间接免疫荧光试验相比，该试验具有敏感性和特异性。对89例有呼吸道症状患者的配对血清进行评估，结果显示东安格利亚地区嗜肺军团菌血清群5呼吸道感染的发生率较低：本研究仅发现1例。RMAT作为常规血清学实验室的筛查试验易于操作。