Harrison T G, Dournon E, Taylor A G
J Clin Pathol. 1987 Jan;40(1):77-82. doi: 10.1136/jcp.40.1.77.
The sensitivity of an indirect immunofluorescence antibody test (IFAT) and a rapid microagglutination test (RMAT) for the diagnosis of Legionnaires' disease caused by Legionella pneumophila serogroup 1 was evaluated using serum specimens from 119 patients with bacteriologically confirmed infections. The sensitivity of both assays was found to be about 80%. In addition, antibody titres suggestive of L pneumophila infection were found in 40% of patients in the first week after admission to hospital. These data show that both assays can be used with confidence in the early diagnosis of Legionnaires' disease.
使用119例细菌学确诊感染患者的血清标本，对间接免疫荧光抗体试验（IFAT）和快速微量凝集试验（RMAT）诊断嗜肺军团菌血清1型引起的军团病的敏感性进行了评估。发现两种检测方法的敏感性均约为80%。此外，在入院后第一周，40%的患者中发现了提示嗜肺军团菌感染的抗体滴度。这些数据表明，这两种检测方法都可放心用于军团病的早期诊断。
