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[风湿性多肌痛和巨细胞动脉炎的诊断与预后]

[Diagnosis and prognosis of polymyalgia rheumatica and giant cell arteritis].

作者信息

ter Maaten J C, van de Kaa C A, Hoorntje S J, Hillen H F

机构信息

Catharina Ziekenhuis, afd. Interne Geneeskunde, Eindhoven.

出版信息

Ned Tijdschr Geneeskd. 1991 Jan 12;135(2):64-8.

PMID:1990310
Abstract

Retrospectively the data were examined of 69 patients with polymyalgia rheumatica (PMR) and giant-cell arteritis (GCA), of whom 62 were treated with corticosteroids. The clinical and laboratory data, and the outcome of temporal artery biopsy were compared. In addition the relation between the course of the disease and survival was investigated. PMR and GCA are closely related syndromes with a multiform clinical presentation. There even is a group of patients with merely systemic symptoms, without specific signs of PMR or GCA. Concerning the course of the disease patients can be divided into groups with a shorter and longer period of disease activity; patients with a smooth stable remission and a chronic disease. The former group shows a significantly better five-year survival. At the time of diagnosis no reliable prediction of the course of the disease is possible.

摘要

回顾性分析了69例风湿性多肌痛(PMR)和巨细胞动脉炎(GCA)患者的数据,其中62例接受了皮质类固醇治疗。比较了临床和实验室数据以及颞动脉活检的结果。此外,还研究了疾病进程与生存率之间的关系。PMR和GCA是密切相关的综合征,临床表现多样。甚至有一组患者仅有全身症状,没有PMR或GCA的特异性体征。关于疾病进程,患者可分为疾病活动期较短和较长的组;病情平稳缓解和慢性病患者。前一组的五年生存率明显更高。在诊断时,无法对疾病进程进行可靠预测。

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