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成年初级视皮层中视野图谱的可塑性与稳定性

Plasticity and stability of visual field maps in adult primary visual cortex.

作者信息

Wandell Brian A, Smirnakis Stelios M

机构信息

Stanford University, Psychology Department, Jordan Hall, Stanford, California 94305, USA.

出版信息

Nat Rev Neurosci. 2009 Dec;10(12):873-84. doi: 10.1038/nrn2741. Epub 2009 Nov 11.

Abstract

It is important to understand the balance between cortical plasticity and stability in various systems and across spatial scales in the adult brain. Here we review studies of adult plasticity in primary visual cortex (V1), which has a key role in distributing visual information. There are claims of plasticity at multiple spatial scales in adult V1, but a number of inconsistencies in the supporting data raise questions about the extent and nature of such plasticity. Our understanding of the extent of plasticity in V1 is further limited by a lack of quantitative models to guide the interpretation of the data. These problems limit efforts to translate research findings about adult cortical plasticity into significant clinical, educational and policy applications.

摘要

了解成人大脑中各种系统以及跨空间尺度下皮质可塑性与稳定性之间的平衡非常重要。在此,我们回顾了初级视觉皮层(V1)中成人可塑性的研究,该区域在视觉信息分配中起关键作用。有观点认为成人V1在多个空间尺度上存在可塑性,但支持数据中的一些不一致之处引发了关于这种可塑性的程度和性质的疑问。我们对V1可塑性程度的理解还因缺乏定量模型来指导数据解释而受到进一步限制。这些问题限制了将关于成人皮质可塑性的研究结果转化为重要临床、教育和政策应用的努力。

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