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多个完全非对称简单排斥过程对有限资源池的竞争。

Competition between multiple totally asymmetric simple exclusion processes for a finite pool of resources.

作者信息

Cook L Jonathan, Zia R K P, Schmittmann B

机构信息

Department of Physics, Virginia Tech, Blacksburg, Virginia 24061, USA.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Sep;80(3 Pt 1):031142. doi: 10.1103/PhysRevE.80.031142. Epub 2009 Sep 28.

Abstract

Using Monte Carlo simulations and a domain-wall theory, we discuss the effect of coupling several totally asymmetric simple exclusion processes (TASEPs) to a finite reservoir of particles. This simple model mimics directed biological transport processes in the presence of finite resources such as protein synthesis limited by a finite pool of ribosomes. If all TASEPs have equal length, we find behavior which is analogous to a single TASEP coupled to a finite pool. For the more generic case of chains with different lengths, several unanticipated regimes emerge. A generalized domain-wall theory captures our findings in good agreement with simulation results.

摘要

利用蒙特卡罗模拟和畴壁理论,我们讨论了将几个完全不对称简单排斥过程(TASEP)与有限粒子库耦合的效应。这个简单模型模拟了在有限资源(如受有限核糖体库限制的蛋白质合成)存在下的定向生物运输过程。如果所有TASEP具有相同长度,我们发现其行为类似于与有限库耦合的单个TASEP。对于不同长度链的更一般情况,出现了几种意想不到的状态。一种广义畴壁理论很好地捕捉了我们的发现,与模拟结果一致。

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