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拉美地区引产相关因素及结局。

Factors and outcomes associated with the induction of labour in Latin America.

机构信息

Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.

出版信息

BJOG. 2009 Dec;116(13):1762-72. doi: 10.1111/j.1471-0528.2009.02348.x.

Abstract

OBJECTIVE

To describe the prevalence of labour induction, together with its risk factors and outcomes in Latin America.

DESIGN

Analysis of the 2005 WHO global survey database.

SETTING

Eight selected Latin American countries.

POPULATION

All women who gave birth during the study period in 120 participating institutions.

METHODS

Bivariate and multivariate analyses.

MAIN OUTCOME MEASURES

Indications for labour induction per country, success rate per method, risk factors for induction, and maternal and perinatal outcomes.

RESULTS

Of the 97,095 deliveries included in the survey, 11,077 (11.4%) were induced, with 74.2% occurring in public institutions, 20.9% in social security hospitals and 4.9% in private institutions. Induction rates ranged from 5.1% in Peru to 20.1% in Cuba. The main indications were premature rupture of membranes (25.3%) and elective induction (28.9%). The success rate of vaginal delivery was very similar for oxytocin (69.9%) and misoprostol (74.8%), with an overall success rate of 70.4%. Induced labour was more common in women over 35 years of age. Maternal complications included higher rates of perineal laceration, need for uterotonic agents, hysterectomy, ICU admission, hospital stay>7 days and increased need for anaesthetic/analgesic procedures. Some adverse perinatal outcomes were also higher: low 5-minute Apgar score, very low birthweight, admission to neonatal ICU and delayed initiation of breastfeeding.

CONCLUSIONS

In Latin America, labour was induced in slightly more than 10% of deliveries; success rates were high irrespective of the method used. Induced labour is, however, associated with poorer maternal and perinatal outcomes than spontaneous labour.

摘要

目的

描述拉丁美洲地区引产的流行情况,及其相关风险因素和结局。

方法

对 2005 年世卫组织全球调查数据库进行分析。

地点

8 个选定的拉丁美洲国家。

人群

120 个参与机构中在研究期间分娩的所有妇女。

设计

描述性分析。

主要结局指标

每个国家的引产指征、每种方法的成功率、引产的风险因素以及母婴结局。

结果

在调查纳入的 97095 例分娩中,有 11077 例(11.4%)接受了引产,其中 74.2%在公立机构进行,20.9%在社会保障医院进行,4.9%在私立机构进行。引产率范围为秘鲁的 5.1%至古巴的 20.1%。主要的引产指征是胎膜早破(25.3%)和选择性引产(28.9%)。催产素(69.9%)和米索前列醇(74.8%)阴道分娩的成功率非常相似,总体成功率为 70.4%。35 岁以上的妇女更常接受引产。产妇并发症包括会阴裂伤、子宫收缩剂、子宫切除、入住 ICU、住院时间>7 天和需要更多麻醉/镇痛的比例增加。一些不良围产儿结局也更高:5 分钟 Apgar 评分低、极低出生体重、入住新生儿 ICU 和母乳喂养延迟。

结论

在拉丁美洲,10%以上的分娩接受了引产;无论采用何种方法,成功率都很高。然而,与自然分娩相比,引产与较差的母婴结局相关。

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