Coste J, Job-Spira N, Fernandez H
INSERM U. 292-Hôpital de Bicêtre, Le Kremlin-Bicetre, France.
Am J Public Health. 1991 Feb;81(2):199-201. doi: 10.2105/ajph.81.2.199.
As part of a case-control study of ectopic pregnancy, we evaluated the potential etiologic role of cigarette smoking. Maternal cigarette smoking at the time of conception was associated with an increased risk of ectopic pregnancy with a dose-response relationship (adjusted odds ratios: 1.30 to 2.49). On the other hand, partner's smoking was not associated with ectopic pregnancy. The study provides a supplementary argument towards a causal effect of smoking in the development of ectopic pregnancy.
作为一项异位妊娠病例对照研究的一部分，我们评估了吸烟的潜在病因学作用。受孕时孕妇吸烟与异位妊娠风险增加相关，且存在剂量反应关系（调整后的优势比：1.30至2.49）。另一方面，伴侣吸烟与异位妊娠无关。该研究为吸烟在异位妊娠发生中的因果效应提供了补充论据。
