Levin A A, Schoenbaum S C, Stubblefield P G, Zimicki S, Monson R R, Ryan K J
Am J Public Health. 1982 Mar;72(3):253-6. doi: 10.2105/ajph.72.3.253.
We compared the prior pregnancy histories of 85 multigravid women with an ectopic pregnancy and 498 multigravid delivery comparison subjects. We found a relationship between the number of prior induced abortions and the risk of ectopic pregnancy: the crude relative risk of ectopic pregnancy was 1.6 for women with one prior induced abortion and 4.0 for women with two or more prior induced abortions; however, use of multivariate techniques to control confounding factors reduced the relative risks to 1.3 (95 per cent confidence interval, 0.6-2.7) and 2.6 (95 per cent confidence interval, 0.9-7.4), respectively. The analysis suggests that induced abortion may be one of several risk factors for ectopic pregnancy, particularly for women who have had abortions plus pelvic inflammatory disease or multiple abortions.
我们比较了85例有异位妊娠史的经产妇和498例经产妇分娩对照对象的既往妊娠史。我们发现既往人工流产次数与异位妊娠风险之间存在关联:既往有1次人工流产的妇女,异位妊娠的粗相对风险为1.6;既往有2次或更多次人工流产的妇女,异位妊娠的粗相对风险为4.0;然而,使用多变量技术控制混杂因素后,相对风险分别降至1.3(95%置信区间为0.6 - 2.7)和2.6(95%置信区间为0.9 - 7.4)。该分析表明,人工流产可能是异位妊娠的若干风险因素之一,尤其是对于那些有流产史加盆腔炎或多次流产的妇女。