成人颅内病变导致的不明原因猝死。
Sudden unexplained death in adults caused by intracranial pathology.
作者信息
Black M, Graham D I
机构信息
Department of Forensic Medicine and Science, University of Glasgow, University Avenue, Glasgow G12 8QQ, Scotland, UK.
出版信息
J Clin Pathol. 2002 Jan;55(1):44-50. doi: 10.1136/jcp.55.1.44.
Abstract
Sudden unexplained deaths as a result of intracranial lesions in adults are an important component of medicolegal practice and are best examined as a combined effort by a forensic pathologist, or a histopathologist experienced in coroner's necropsies, and a neuropathologist. Analysis of case material on file in the University of Glasgow's departments of forensic medicine and science, and neuropathology showed that the principal causes were sudden unexplained death in epilepsy (SUDEP), intracranial haemorrhage, either natural or after trauma, purulent meningitis or an abscess, and tumours. The mechanisms of death are considered to be the rapid increase of intracranial pressure caused by bleeding into the various compartments of the brain, or an acute obstructive hydrocephalus, and in cases where death is very rapid, autonomic and/or neurochemical dysfunction.
摘要
成人因颅内病变导致的不明原因猝死是法医学实践的一个重要组成部分，最好由法医病理学家、或有验尸经验的组织病理学家以及神经病理学家共同进行检查。对格拉斯哥大学法医学与科学系以及神经病理学系存档的病例资料分析表明，主要病因包括癫痫猝死（SUDEP）、自然性或外伤性颅内出血、化脓性脑膜炎或脓肿以及肿瘤。死亡机制被认为是血液流入脑内各个腔隙导致颅内压迅速升高、或急性梗阻性脑积水，而在死亡非常迅速的情况下，则是自主神经和/或神经化学功能障碍。
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本文引用的文献
1
Pathology of sudden death.猝死的病理学
Lancet. 1947 Nov 22;2(6482):745-7. doi: 10.1016/s0140-6736(47)90759-9.
2
Sudden unexpected death in epilepsy: terminology and definitions.癫痫相关性猝死：术语与定义。
Epilepsia. 1997 Nov;38(11 Suppl):S6-8. doi: 10.1111/j.1528-1157.1997.tb06130.x.
3
Recording respiratory parameters in patients with epilepsy.记录癫痫患者的呼吸参数。
Epilepsia. 1997 Nov;38(11 Suppl):S41-2. doi: 10.1111/j.1528-1157.1997.tb06126.x.
4
Neuropathologic findings in postmortem studies of sudden death in epilepsy.尸检研究中癫痫猝死的神经病理学发现。
Epilepsia. 1997 Nov;38(11 Suppl):S32-4. doi: 10.1111/j.1528-1157.1997.tb06123.x.
5
Epilepsy and sudden death: a personal view.癫痫与猝死：个人观点。
Epilepsia. 1997 Nov;38(11 Suppl):S3-5. doi: 10.1111/j.1528-1157.1997.tb06121.x.
6
The mortality associated with epilepsy, with particular reference to sudden unexpected death: a review.癫痫相关死亡率，特别关注突发性意外死亡：综述。
Epilepsia. 1997 Nov;38(11 Suppl):S15-9. doi: 10.1111/j.1528-1157.1997.tb06117.x.
7
294 MEDICOLEGAL AUTOPSIES ON EPILEPTICS, CEREBRAL FINDINGS.
Arch Pathol. 1964 Sep;78:274-86.
8
Sudden or unexpected natural death due to ruptured intracranial aneurysm; survey of 250 forensic cases.颅内动脉瘤破裂导致的突然或意外自然死亡；250例法医案例调查
Lancet. 1953 Oct 17;265(6790):799-801. doi: 10.1016/s0140-6736(53)90467-x.
9
Sudden unexpected death in epilepsy.癫痫所致的意外猝死。
Postgrad Med J. 1999 Dec;75(890):706-9. doi: 10.1136/pgmj.75.890.706.
10
Sudden unexpected death in epilepsy (SUDEP): a clinical perspective and a search for risk factors.癫痫猝死（SUDEP）：临床视角及危险因素探寻
J Neurol Neurosurg Psychiatry. 1999 Oct;67(4):439-44. doi: 10.1136/jnnp.67.4.439.
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