Department of Epidemiology, Local Health Authority Rome E, Rome, Italy.
Environ Health. 2009 Nov 12;8:50. doi: 10.1186/1476-069X-8-50.
Few studies have identified specific factors that increase mortality during heat waves. This study investigated socio-demographic characteristics and pre-existing medical conditions as effect modifiers of the risk of dying during heat waves in a cohort of elderly residents in Rome.
A cohort of 651,195 residents aged 65 yrs or older was followed from 2005 to 2007. During summer, heat wave days were defined according to month-specific thresholds of maximum apparent temperature. The adjusted relative risk of dying during heat waves was estimated using a Poisson regression model including all the considered covariates. Risk differences were also calculated. All analyses were run separately for the 65-74 and 75+ age groups.
In the 65-74 age group the risk of dying during heat waves was higher among unmarried subjects and those with a previous hospitalization for chronic pulmonary disease or psychiatric disorders. In the 75+ age group, women, and unmarried subjects were more susceptible to heat. Furthermore, a higher susceptibility to heat among those with previous hospitalization for diabetes, diseases of the central nervous system (CNS), psychiatric disorders and cerebrovascular diseases resulted from risk differences.
Results showed a higher susceptibility to heat among those older than seventy-five years, females and unmarried. Pre-existing health conditions play a different role among the two considered age groups. Moreover, compared with previous studies the pattern of susceptibility factors have slightly changed over time. For the purposes of public health programmes, susceptibility should be considered as time, space and population specific.
很少有研究确定了在热浪期间增加死亡率的具体因素。本研究调查了社会人口统计学特征和预先存在的医疗状况,作为罗马老年居民队列中热浪期间死亡风险的效应修饰剂。
一项由 651195 名 65 岁或以上居民组成的队列从 2005 年至 2007 年进行了随访。在夏季,根据最大表观温度的特定月份阈值定义了热浪日。使用包含所有考虑因素的泊松回归模型估计热浪期间死亡的调整相对风险。还计算了风险差异。所有分析均分别在 65-74 岁和 75+岁年龄组中进行。
在 65-74 岁年龄组中,未婚者和先前因慢性肺部疾病或精神疾病住院的人在热浪期间死亡的风险更高。在 75+岁年龄组中,女性和未婚者更容易受到高温的影响。此外,先前因糖尿病、中枢神经系统 (CNS) 疾病、精神疾病和脑血管疾病住院的人因风险差异而更容易受到高温的影响。
结果表明,75 岁以上的人、女性和未婚者更容易受到高温的影响。预先存在的健康状况在两个考虑的年龄组中起着不同的作用。此外,与以前的研究相比,易感性因素的模式随着时间的推移略有变化。对于公共卫生计划,易感性应被视为特定于时间、空间和人群的因素。