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静脉性腿部溃疡:患者对加压治疗的依从性及其对愈合和复发预防的影响。

Venous leg ulcers: patient concordance with compression therapy and its impact on healing and prevention of recurrence.

机构信息

Glasgow University Medical School, Glasgow, UK and Cardiff School of Medicine, Cardiff, UK.

出版信息

Int Wound J. 2009 Oct;6(5):386-93. doi: 10.1111/j.1742-481X.2009.00634.x.

DOI:10.1111/j.1742-481X.2009.00634.x
PMID:19912396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7951474/
Abstract

Moffatt Christine, Kommala Dheerendra, Dourdin Nathalie, Choe Yoonhee. Venous leg ulcers: patient concordance with compression therapy and its impact on healing and prevention of recurrence. ABSTRACT This study aimed to review available data on the reasons attributed to patient non concordance with compression therapy for the treatment of venous leg ulcers (VLUs), the frequency of non concordance and its effects on clinical outcomes. The biomedical literature was searched for publications on VLUs, compression therapy and concordance over the past 20 years. Physical, aesthetic and cosmetic factors, patient lack of education about VLUs, cost of therapy and issues with treatment by clinicians were all reported to influence concordance with compression therapy. The search identified 10 studies reporting patient concordance with compression stockings or bandages; while non concordance ranged from 2% to 42% of patients in three randomised controlled trials, it was generally higher in real-world studies, ranging from 9.7% to 80%. Another set of six studies indicated that the healing rate was half and the median time to complete healing was twice as long when patients were not concordant. Further, recurrence rates were 2-20 times greater when patients did not comply with the use of stockings following VLU healing. In conclusion, published biomedical literature has documented that non concordance with compression therapy negatively impacts the outcome of VLUs, highlighting the need to improve patient concordance to maximise therapeutic benefits.

摘要

莫法特·克里斯汀、科马拉·迪尔恩德拉、多尔丁·纳塔莉、崔允熙。静脉性腿部溃疡:患者对加压治疗的依从性及其对愈合和预防复发的影响。摘要 本研究旨在回顾过去 20 年中有关患者对静脉性腿部溃疡(VLU)治疗的加压治疗依从性的原因、不依从的频率及其对临床结果的影响的相关数据。对有关静脉溃疡、加压治疗和一致性的生物医学文献进行了检索。身体、美学和美容因素、患者对 VLU 的教育缺乏、治疗费用以及临床医生治疗问题都被认为会影响对加压治疗的依从性。该检索确定了 10 项报告患者对压缩袜或绷带依从性的研究;虽然三项随机对照试验中有 2%至 42%的患者不依从,但在真实世界的研究中通常更高,范围从 9.7%至 80%。另外 6 项研究表明,当患者不依从时,愈合率减半,完全愈合的中位数时间延长一倍。此外,当患者在 VLU 愈合后不遵守使用袜子时,复发率增加 2 至 20 倍。总之,已发表的生物医学文献记录了不依从加压治疗会对 VLU 的结果产生负面影响,这突出表明需要提高患者的依从性以最大程度地提高治疗效果。

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本文引用的文献

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Variability of pressure provided by sustained compression.持续压迫所提供压力的变异性。
Int Wound J. 2008 Jun;5(2):259-65. doi: 10.1111/j.1742-481X.2008.00470.x.
2
Intermittent pneumatic compression for treating venous leg ulcers.间歇性气动压迫治疗下肢静脉溃疡
Cochrane Database Syst Rev. 2008 Apr 16(2):CD001899. doi: 10.1002/14651858.CD001899.pub2.
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Efficacy, safety and acceptability of a new two-layer bandage system for venous leg ulcers.一种新型双层绷带系统用于下肢静脉性溃疡的疗效、安全性及可接受性
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A systematic review on the impact of leg ulceration on patients' quality of life.关于腿部溃疡对患者生活质量影响的系统评价。
Health Qual Life Outcomes. 2007 Jul 25;5:44. doi: 10.1186/1477-7525-5-44.
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Compression modalities and dressings: their use in venous ulcers.压迫方式与敷料:它们在静脉性溃疡中的应用
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Prevention of recurrence of venous ulceration: randomized controlled trial of class 2 and class 3 elastic compression.预防静脉溃疡复发:2级和3级弹性压迫的随机对照试验
J Vasc Surg. 2006 Oct;44(4):803-8. doi: 10.1016/j.jvs.2006.05.051.