Amrita Centre for Nanosciences and Molecular Medicine, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidhyapeetham University, Cochin-682 041, India.
Biotechnol Adv. 2010 Jan-Feb;28(1):142-50. doi: 10.1016/j.biotechadv.2009.11.001.
Chitin and its deacetylated derivative, chitosan, are non-toxic, antibacterial, biodegradable and biocompatible biopolymers. Due to these properties, they are widely used for biomedical applications such as tissue engineering scaffolds, drug delivery, wound dressings, separation membranes and antibacterial coatings, stent coatings, and sensors. In the recent years, electrospinning has been found to be a novel technique to produce chitin and chitosan nanofibers. These nanofibers find novel applications in biomedical fields due to their high surface area and porosity. This article reviews the recent reports on the preparation, properties and biomedical applications of chitin and chitosan based nanofibers in detail.
几丁质及其脱乙酰衍生物壳聚糖是无毒、抗菌、可生物降解和生物相容的生物聚合物。由于这些特性，它们被广泛应用于生物医学领域，如组织工程支架、药物输送、伤口敷料、分离膜和抗菌涂层、支架涂层和传感器。近年来，静电纺丝已被发现是一种生产几丁质和壳聚糖纳米纤维的新技术。由于其高表面积和多孔性，这些纳米纤维在生物医学领域有新的应用。本文详细综述了近年来关于基于几丁质和壳聚糖的纳米纤维的制备、性能及在生物医学方面的应用的研究进展。
Biotechnol Adv. 2010
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