Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Adv Drug Deliv Rev. 2010 Mar 8;62(3):316-28. doi: 10.1016/j.addr.2009.11.004. Epub 2009 Nov 11.
Nanoparticle based platforms for identification of chemical and biological agents offer substantial benefits to biomedical and environmental science. These platforms benefit from the availability of a wide variety of core materials as well as the unique physical and chemical properties of these nanoscale materials. This review surveys some of the emerging approaches in the field of nanoparticle based detection systems, highlighting the nanoparticle based screening methods for metal ions, proteins, nucleic acids, and biologically relevant small molecules.
基于纳米粒子的化学和生物制剂识别平台为生物医学和环境科学提供了实质性的好处。这些平台得益于各种核心材料的可用性，以及这些纳米级材料的独特物理和化学性质。本文综述了基于纳米粒子的检测系统领域的一些新兴方法，重点介绍了基于纳米粒子的金属离子、蛋白质、核酸和生物相关小分子的筛选方法。
