Goldberg J M, Miller F A, Friedman C I, Dodds W G, Kim M H
Ohio State University, Columbus.
Fertil Steril. 1991 Feb;55(2):319-23. doi: 10.1016/s0015-0282(16)54123-5.
The presence of ovarian cysts may compromise the success of in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT). We prospectively studied 212 consecutive ovulation induction cycles in 120 patients for IVF and/or GIFT. A baseline cyst was defined as any intraovarian cystic structure greater than or equal to 12 mm noted on ultrasonography before superovulation. Cycle outcomes were compared between patients with cysts (n = 62) versus those with no cysts (n = 150). There were no differences in follicular or luteal phase lengths or amount of human menopausal gonadotropins used. Peak estradiol (E2) levels were significantly lower and cancellation rates significantly higher in the cyst group. For noncanceled cycles, there were no significant differences in peak E2 levels, the mean number of follicles greater than or equal to 12 mm, mature oocytes retrieved, or ova transferred for GIFT or embryos for IVF. The pregnancy rates overall and for noncanceled cycles were not significantly different.
卵巢囊肿的存在可能会影响体外受精（IVF）和配子输卵管内移植（GIFT）的成功率。我们对120例接受IVF和/或GIFT的患者连续进行了212个促排卵周期的前瞻性研究。基线囊肿定义为在超排卵前超声检查发现的任何直径大于或等于12 mm的卵巢内囊性结构。比较了有囊肿患者（n = 62）和无囊肿患者（n = 150）的周期结局。两组在卵泡期或黄体期长度以及使用的人绝经期促性腺激素剂量方面没有差异。囊肿组的雌二醇（E2）峰值水平显著较低，取消率显著较高。对于未取消的周期，在E2峰值水平、直径大于或等于12 mm的卵泡平均数量、获取的成熟卵母细胞数量、GIFT移植的卵子数量或IVF移植的胚胎数量方面没有显著差异。总体妊娠率和未取消周期的妊娠率没有显著差异。
