Pouly J L, Janny L, Canis M, Vye P, Boyer C
Service de Gynécologie et Obstétrique, Polyclinique Phillipe Marcombes, Centre Hospitalier et Universitaire, Clermont Ferrand, France.
Fertil Steril. 1989 Dec;52(6):1012-7. doi: 10.1016/s0015-0282(16)53167-7.
Fifty-six cycles of gamete intrafallopian transfer (GIFT) were performed after programming by administration of norethisterone in the previous cycle. Ovarian hyperstimulation was achieved with clomifene citrate and human menopausal gonadotropins. Only one GIFT was performed during a weekend (1.8%). The implantation rate was 41.1% and the evolutive pregnancy rate 30.4%. The endocrinological influence of these regimens are discussed by comparison of those observed in an in vitro fertilization program. The main influence is a decreased serum luteinizing hormone (LH) level in the preovulatory phase.
在前一周期服用炔诺酮进行预处理后,进行了56个周期的配子输卵管内移植(GIFT)。使用枸橼酸氯米芬和人绝经期促性腺激素实现卵巢过度刺激。仅在一个周末进行了1次GIFT(1.8%)。着床率为41.1%,妊娠进展率为30.4%。通过与体外受精程序中观察到的情况进行比较,讨论了这些方案的内分泌影响。主要影响是排卵前期血清促黄体生成素(LH)水平降低。