人类精子中血小板活化因子样活性的存在。

The presence of platelet-activating factor-like activity in human spermatozoa.

作者信息

Minhas B S, Kumar R, Ricker D D, Robertson J L, Dodson M G

机构信息

Department of Obstetrics and Gynecology, East Tennessee State University, James H. Quillen College of Medicine, Johnson City 37614.

出版信息

Fertil Steril. 1991 Feb;55(2):372-6. doi: 10.1016/s0015-0282(16)54132-6.

DOI:10.1016/s0015-0282(16)54132-6

PMID:1991535

Abstract

Evidence is provided for the existence of platelet-activating factor (PAF)-like activity in the lipid extracts of human spermatozoa. The PAF content of human spermatozoa based on [3H]-serotonin release from washed rabbit platelets was noted to be 1.45 pmol/10(8) sperm cells in highly purified motile spermatozoa. No PAF activity was associated with the seminal fluid. Platelet-activating factor content of spermatozoa may be related to its fertility potential.

摘要

有证据表明人类精子的脂质提取物中存在类似血小板活化因子（PAF）的活性。基于从洗涤过的兔血小板中释放[3H] - 血清素，在高度纯化的有活力精子中，人类精子的PAF含量为1.45 pmol/10(8)个精子细胞。精液中未发现PAF活性。精子中的血小板活化因子含量可能与其生育潜力有关。