Mueller Edgar A, Kirch Wilhelm
Institut für Klinische Pharmakologie, Medizinische Fakultät, Technische Universität Dresden, Dresden, Germany.
Med Klin (Munich). 2009 Nov 15;104(11):846-50. doi: 10.1007/s00063-009-1181-9. Epub 2009 Nov 17.
Errors can occur at any time during drug therapy. A not inconsiderable percentage of hospital admissions to internal medicine departments are caused by adverse drug events (ADEs), many of which could be avoided. Avoidable ADEs mainly result from suboptimal procedures in the medication process. In order to recognize and minimize these risks, cooperative interaction of all those involved in the medication process is required. This also includes involving patients. A plan of action to improve safety of drug therapy in Germany has recently been completed under the aegis of the Federal Ministry of Health. In a concerted effort, structures and procedures of pharmacotherapy are to be systematically analyzed and improved. The plan of action is focused on measures that can be achieved in the short term, with particular emphasis on the reduction of risks.
The purpose of this paper is to make a contribution to increasing the patients' awareness for the risks associated with drug therapy and to provide suggestions of what they can do to improve the safety of their own therapy.
With relatively simple means, patients can make an important contribution to improving the safety of drug therapy. However, only a collective increased sensitization for potential medication errors can lead to a sustainable risk reduction.
药物治疗过程中的任何时候都可能出现差错。内科病房相当一部分住院病例是由药物不良事件（ADEs）引起的，其中许多是可以避免的。可避免的药物不良事件主要源于用药过程中的欠佳程序。为了识别并将这些风险降至最低，需要参与用药过程的所有人员进行协作互动。这也包括让患者参与进来。在联邦卫生部的支持下，德国近期完成了一项旨在提高药物治疗安全性的行动计划。各方共同努力，将对药物治疗的结构和程序进行系统分析并加以改进。该行动计划侧重于短期内能够实现的措施，尤其强调降低风险。
本文旨在为提高患者对药物治疗相关风险的认识做出贡献，并就患者如何提高自身治疗安全性提出建议。
通过相对简单的方法，患者能够为提高药物治疗安全性做出重要贡献。然而，只有集体提高对潜在用药差错的敏感度，才能实现风险的持续降低。
