Department of clinical science, Obstetrics and gynecology, Umeå University, Sweden.
BMC Pregnancy Childbirth. 2009 Nov 16;9:53. doi: 10.1186/1471-2393-9-53.
Screening for gestational diabetes mellitus (GDM) is routine during pregnancy in many countries in the world. The screening programs are either based on general screening offered to all pregnant women or risk factor based screening stipulated in local clinical guidelines. The aims of this study were to investigate: 1) the compliance with local guidelines of screening for GDM and 2) the outcomes of pregnancy and birth in relation to risk factors of GDM and whether or not exposed to oral glucose tolerance test (OGTT).
This study design was a population-based retrospective cross-sectional study of 822 women. A combination of questionnaire data and data collected from medical records was applied. Compliance to the local guidelines of risk factor based screening for GDM was examined and a comparison of outcomes of pregnancy and delivery in relation to risk factor groups for GDM was performed.
Of the 822 participants, 257 (31.3%) women fulfilled at least one criterion for being exposed to screening for GDM according to the local clinical guidelines. However, only 79 (30.7%) of these women were actually exposed to OGTT and of those correctly exposed for screening, seven women were diagnosed with GDM. Women developing risk factors for GDM during pregnancy had a substantially increased risk of giving birth to an infant with macrosomia.
Surprisingly low compliance with the local clinical guidelines for screening for GDM during pregnancy was found. Furthermore, the prevalence of the risk factors of GDM in our study was almost doubled compared to previous Swedish studies. Pregnant women developing risk factors of GDM during pregnancy were found to be at substantially increased risk of giving birth to an infant with macrosomia. There is a need of actions improving compliance to the local guidelines.
在世界上许多国家,妊娠期糖尿病(GDM)筛查是孕期常规检查。筛查方案有两种:一种是针对所有孕妇的一般筛查;另一种是基于当地临床指南规定的危险因素筛查。本研究旨在调查:1)筛查 GDM 对当地指南的依从性;2)GDM 危险因素及是否接受口服葡萄糖耐量试验(OGTT)与妊娠和分娩结局的关系。
本研究是一项基于人群的回顾性横断面研究,共纳入 822 名女性。采用问卷调查和病历资料相结合的方法。对基于危险因素的 GDM 筛查当地指南的依从性进行了检查,并对 GDM 危险因素组的妊娠和分娩结局进行了比较。
在 822 名参与者中,根据当地临床指南,有 257 名(31.3%)女性至少符合 GDM 筛查标准。然而,只有 79 名(30.7%)女性实际上接受了 OGTT 检查,而在这些正确接受筛查的女性中,有 7 人被诊断为 GDM。在孕期出现 GDM 危险因素的女性,其分娩巨大儿的风险显著增加。
令人惊讶的是,我们发现对孕期 GDM 筛查当地临床指南的依从性很低。此外,与之前的瑞典研究相比,我们研究中 GDM 危险因素的患病率几乎翻了一番。在孕期出现 GDM 危险因素的孕妇,其分娩巨大儿的风险显著增加。需要采取措施提高对当地指南的依从性。