Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Mol Cell. 2009 Nov 13;36(3):351-2. doi: 10.1016/j.molcel.2009.10.026.
In this issue of Molecular Cell, Ide et al. (2009) have identified the enzyme guanidinoacetate methyltransferase (GAMT) that regulates creatine metabolism as a p53 target involved in apoptosis, reactive oxygen species (ROS), and fatty acid metabolism.
在本期《分子细胞》中,Ide 等人(2009 年)鉴定出调节肌酸代谢的酶胍基乙酸甲基转移酶(GAMT)是参与细胞凋亡、活性氧(ROS)和脂肪酸代谢的 p53 靶标。