通过克隆的purA基因抑制大肠杆菌K-12的rdgB突变体中的缺陷。
Suppression of the defects in rdgB mutants of Escherichia coli K-12 by the cloned purA gene.
作者信息
Clyman J, Cunningham R P
机构信息
Department of Biological Sciences, State University of New York, Albany 12222.
出版信息
J Bacteriol. 1991 Feb;173(3):1360-2. doi: 10.1128/jb.173.3.1360-1362.1991.
Abstract
A gene suppressing the defects of Escherichia coli rdgB (recA-dependent growth) and recA(Ts) rdgB mutants was cloned. The cloned gene suppresses the hyper-Rec phenotype and the enhanced level of SOS functions in rdgB mutants at the nonpermissive temperature. We identified the cloned gene as purA.
摘要
克隆到一个抑制大肠杆菌rdgB（recA依赖性生长）和recA（Ts）rdgB突变体缺陷的基因。该克隆基因在非允许温度下可抑制rdgB突变体中的高Rec表型和SOS功能增强水平。我们鉴定该克隆基因是purA。
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