Department of Oral and Maxillofacial Surgery, Pastic Surgery, Fachklinik Hornheide, Münster, Germany.
Int J Prosthodont. 2009 Nov-Dec;22(6):594-6.
This study sought to develop treatment strategies for managing percutaneous infection around craniofacial implants. The present general pathogen situation together with a bacterial resistance were determined in 57 infected peri-implant sites. Forty-four implants were randomly assigned for wound cleaning and split into three groups-two with local antibiotics of proven efficacy and one with 3% hydrogen peroxide (H2O2). The pathogen spectrum differed depending on the severity of the infection, with Staphylococcus aureus clearly correlated with the degree of inflammation (positive correlation: R = 0.72). It was observed that the use of additional local antibiotics was not superior to conventional wound cleaning with 3% H2O2. It is suggested that sulcus fluid flow rate measurements could serve as a simple and reliable objective parameter for recall examinations.
本研究旨在为处理颅面植入物周围经皮感染制定治疗策略。本研究共检测了 57 个感染种植体周围部位，以确定目前的一般病原体情况和细菌耐药性。将 44 个种植体随机分为三组进行伤口清洗，其中两组使用已证实有效的局部抗生素，一组使用 3%过氧化氢（H2O2）。病原体谱因感染严重程度而异，金黄色葡萄球菌与炎症程度呈明显正相关（相关系数：R = 0.72）。结果表明，与传统的 3%H2O2 冲洗相比，使用额外的局部抗生素并不优于传统的 3%H2O2 冲洗。研究表明，龈沟液流速测量可以作为一种简单、可靠的客观参数，用于复诊检查。
