Princess Alexandra Eye Pavilion, Edinburgh Royal Infirmary, Edinburgh, Scotland.
J Glaucoma. 1995 Jun;4(3):214-8.
Langham adapted the pneumotonometer to provide a waveform of the ocular pulse and using the heart rate derived values for pulsatile ocular blood flow. We have used a new pneumotonometer linked to an ocular blood flow system that has addressed several of the problems encountered with the Langham technique.
The reproducibility of this new method was assessed by measuring pulsatile ocular blood flow (mul/min) five times on one eye of 20 normal healthy volunteers (mean age 40 years; range 26-62) at one examination session. The test was conducted in the sitting position with the pneumotonometer probe mounted on a slit-lamp microscope.
The mean pulsatile ocular blood flow was 633 +/- 180 mu/min. Statistical analysis using the intraclass correlation method showed there were no significant differences due to sessions for five recordings (p = 0.15) or, after excluding the two most extreme values, for three recordings (p = 0.49). There was no correlation noted between pulsatile ocular blood flow and age in a larger group (n = 49) of normal volunteers (mean age 61 years; range 26-72).
We conclude that pulsatile ocular blood flow measurements with this new instrument are reproducible and may be applied to blood flow studies in ocular hypertension and glaucoma.
朗厄姆（Langham）对眼压计进行了改良，以提供眼脉冲的波形，并利用心率得出的搏动性眼血流值。我们使用了一种新的眼压计，该眼压计与眼血流系统相连，解决了朗厄姆技术遇到的几个问题。
我们在一次检查中，对 20 名健康志愿者（平均年龄 40 岁；范围 26-62 岁）的一只眼睛进行了五次测量，评估了这种新方法的可重复性。该测试在坐姿下进行，眼压计探头安装在裂隙灯显微镜上。
平均搏动性眼血流为 633 ± 180 μl/min。使用组内相关法进行的统计学分析显示，五次记录的会话（p = 0.15）或排除两个极值后的三次记录（p = 0.49）均无显著差异。在更大的正常志愿者组（n = 49）中，年龄与搏动性眼血流之间无相关性（平均年龄 61 岁；范围 26-72 岁）。
我们得出结论，该新仪器的搏动性眼血流测量值具有可重复性，可应用于眼压升高和青光眼的血流研究。
