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意大利欧亚系和美洲系禽流感病毒基因片段重配。

Gene segment reassortment between Eurasian and American clades of avian influenza virus in Italy.

机构信息

OIE/FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Padova, Italy.

出版信息

Arch Virol. 2010;155(1):77-81. doi: 10.1007/s00705-009-0550-2. Epub 2009 Nov 19.

Abstract

All genes of avian influenza A viruses are phylogenetically distinguished into two large clades, namely the American and Eurasian clade. Reassortments among the gene segments of influenza viruses belonging to the two distinct clades are rare events and have never been described in poultry in Europe and Asia before. This study presents the genetic characterization of two influenza viruses isolated from domestic mallards in Italy in 2004 and 2005. Phylogenetic analysis of the entire genome showed that these viruses contain mixed gene segments belonging to the American and Eurasian clades.

摘要

所有禽流感 A 病毒的基因在系统发生上可分为两个大分支,即美洲分支和欧亚分支。属于这两个不同分支的流感病毒基因片段之间的重组是罕见事件,此前从未在欧洲和亚洲的家禽中描述过。本研究介绍了 2004 年和 2005 年从意大利家养野鸭中分离到的两种流感病毒的遗传特征。对整个基因组的系统发生分析表明,这些病毒含有混合的基因片段,属于美洲分支和欧亚分支。

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