非甾体抗炎药会加重炎症性肠病吗？
Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease?
机构信息
Divisions of Gastroenterology (111B1) and Hepatology, VA North Texas Health Care System and the University of Texas Southwestern Medical Center at Dallas, 4500 South Lancaster Road, Dallas, TX 75216, USA.
出版信息
Dig Dis Sci. 2010 Feb;55(2):226-32. doi: 10.1007/s10620-009-1042-7.
PMID:19924534
Abstract
The safety of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with inflammatory bowel disease (IBD) remains unclear. This report discusses potential mechanisms whereby NSAIDs might exacerbate IBD and reviews the available clinical data on the role of NSAIDs in causing exacerbations of ulcerative colitis (UC) and Crohn's disease (CD).
摘要
非甾体抗炎药（NSAIDs）在炎症性肠病（IBD）患者中的安全性尚不清楚。本报告讨论了 NSAIDs 可能使 IBD 恶化的潜在机制，并回顾了 NSAIDs 在溃疡性结肠炎（UC）和克罗恩病（CD）恶化中作用的现有临床数据。
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