Department of Telecommunication Engineering, Jiangsu University, Zhenjiang, China.
Int J Hyperthermia. 2009;25(6):434-45. doi: 10.1080/02656730903061609.
Artificial left-handed metamaterial (LHM) provides a new perspective for microwave hyperthermia. Four flat LHM slab lenses can be used to form a focus-flexible applicator for breast tumour hyperthermia. By adjusting microwave sources behind the four flat LHM lenses, microwaves emitted from the sources can be focused tightly at different points in the breast tissue so that necessary heating depth in breast tissue can be achieved. Numerical simulations with a two-dimensional finite-difference time-domain method indicate that hyperthermia with the proposed four-lens applicator of moderate LHM losses could be effective in achieving desired power deposition in a heterogeneous breast model. Temperature distribution obtained by solving the bio-heat transfer equation demonstrates that temperature above 43 degrees C can be maintained in the tumour volume for specific periods of time. Flat slab LHM lenses offer a feasible alternative to traditional mechanically scanned lens applicator and electronically scanned phased-array applicators.
人工左手性超材料（LHM）为微波热疗提供了新的视角。四个平板 LHM 透镜可用于形成用于乳房肿瘤热疗的灵活聚焦装置。通过调整四个平板 LHM 透镜后面的微波源，从源发出的微波可以在乳房组织的不同点紧密聚焦，从而在乳房组织中达到所需的加热深度。二维有限差分时域方法的数值模拟表明，使用具有适度 LHM 损耗的四透镜装置进行热疗，可以在不均匀的乳房模型中有效地实现所需的功率沉积。通过求解生物传热方程得到的温度分布表明，在特定时间内，肿瘤体积内的温度可以保持在 43 摄氏度以上。平板 LHM 透镜为传统的机械扫描透镜装置和电子扫描相控阵装置提供了一种可行的替代方案。
