Yeh M M, Trembly B S, Douple E B, Ryan T P, Hoopes P J, Jonsson E, Heaney J A
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755.
IEEE Trans Biomed Eng. 1994 Sep;41(9):874-82. doi: 10.1109/10.312095.
An intracavitary microwave antenna array system has been developed and tested for the hyperthermia treatment of prostate cancer at Thayer School of Engineering and Dartmouth-Hitchcock Medical Center. The antenna array consists of a choked dipole antenna inserted into the urethra and a choked dipole antenna eccentrically embedded in a Teflon obturator inserted into the rectum. To prevent unnecessary heating of the healthy tissue that surrounds each applicator, an air cooling system has been incorporated into the rectal applicator. The air cooling system was designed and modeled theoretically using a numerical solution of heat and momentum equations within the applicator, and an analytical solution of the Pennes bioheat equation in tissue surrounding the applicator. The 3-D temperature distribution produced by the air-cooled rectal applicator was measured in a perfused canine prostate.
在达特茅斯学院工程学院和达特茅斯-希区柯克医疗中心,已经开发并测试了一种腔内微波天线阵列系统,用于前列腺癌的热疗。该天线阵列由一个插入尿道的扼流偶极子天线和一个偏心嵌入插入直肠的聚四氟乙烯闭塞器中的扼流偶极子天线组成。为防止每个施源器周围的健康组织出现不必要的发热,直肠施源器中集成了一个空气冷却系统。空气冷却系统是通过对施源器内热和动量方程的数值解以及施源器周围组织中彭尼斯生物热方程的解析解进行理论设计和建模的。在灌注的犬前列腺中测量了风冷直肠施源器产生的三维温度分布。