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在视神经头部水平应用共焦激光扫描多普勒血流计的基本技术和解剖学限制。

Basic technique and anatomically imposed limitations of confocal scanning laser Doppler flowmetry at the optic nerve head level.

机构信息

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA.

出版信息

Acta Ophthalmol. 2011 Feb;89(1):e1-11. doi: 10.1111/j.1755-3768.2009.01728.x.

DOI:10.1111/j.1755-3768.2009.01728.x
PMID:19925515
Abstract

Many studies have suggested an association between blood flow dysregulation and glaucomatous damage to the optic nerve. Confocal scanning laser Doppler flowmetry (CSLDF) is a technique that measures the capillary blood flow of the retina and optic nerve head and provides a two-dimensional map of ocular perfusion in these areas. This review discusses the anatomy of the anterior optic nerve vasculature and the capabilities and limitations of the CSLDF. Methods to minimize error and to acquire more reliable measurements of capillary blood flow are also outlined.

摘要

许多研究表明,血流调节异常与青光眼对视神经的损害之间存在关联。共焦激光扫描多普勒血流计(CSLDF)是一种测量视网膜和视乳头毛细血管血流的技术,可提供这些区域眼灌注的二维图。本文讨论了前视神经血管解剖结构以及 CSLDF 的功能和局限性。还概述了减小误差和获得更可靠毛细血管血流测量值的方法。

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Basic technique and anatomically imposed limitations of confocal scanning laser Doppler flowmetry at the optic nerve head level.在视神经头部水平应用共焦激光扫描多普勒血流计的基本技术和解剖学限制。
Acta Ophthalmol. 2011 Feb;89(1):e1-11. doi: 10.1111/j.1755-3768.2009.01728.x.
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Current Imaging Modalities for assessing Ocular Blood Flow in Glaucoma.评估青光眼眼部血流的当前成像方式
J Curr Glaucoma Pract. 2016 Sep-Dec;10(3):104-112. doi: 10.5005/jp-journals-10008-1210. Epub 2016 Oct 29.
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Reductions in Retrobulbar and Retinal Capillary Blood Flow Strongly Correlate With Changes in Optic Nerve Head and Retinal Morphology Over 4 Years in Open-angle Glaucoma Patients of African Descent Compared With Patients of European Descent.与欧洲裔患者相比,非洲裔开角型青光眼患者4年期间球后和视网膜毛细血管血流减少与视神经乳头和视网膜形态变化密切相关。
J Glaucoma. 2016 Sep;25(9):750-7. doi: 10.1097/IJG.0000000000000520.
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J Coupled Syst Multiscale Dyn. 2013 Apr 1;1(1):1-21. doi: 10.1166/jcsmd.2013.1004.
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