Department of Radiology, RenJi Hospital, Jiao Tong University Medical School, Shanghai 200127, PR China.
Eur J Radiol. 2011 Jul;79(1):92-5. doi: 10.1016/j.ejrad.2009.10.025. Epub 2009 Nov 18.
This study aims to investigate brain gray matter density (GMD) changes in adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on high-resolution T1-weighted structural magnetic resonance images.
Eighteen IA adolescents and 15 age- and gender-matched healthy controls took part in this study. High-resolution T1-weighted magnetic resonance imaging scans were performed on the two groups. VBM analysis was used to compare the GMD between the two groups.
Compared with healthy controls, IA adolescents had lower GMD in the left anterior cingulate cortex, left posterior cingulate cortex, left insula, and left lingual gyrus.
Our findings suggested that brain structural changes were present in IA adolescents, and this finding may provide a new insight into the pathogenesis of IA.
本研究旨在通过基于体素的形态测量学（VBM）分析高分辨率 T1 加权结构磁共振成像，研究青少年网络成瘾（IA）的脑灰质密度（GMD）变化。
18 名 IA 青少年和 15 名年龄和性别匹配的健康对照组参与了本研究。对两组进行高分辨率 T1 加权磁共振成像扫描。采用 VBM 分析比较两组 GMD。
与健康对照组相比，IA 青少年的左前扣带回、左后扣带回、左岛叶和左舌回的 GMD 较低。
我们的研究结果表明，IA 青少年存在脑结构变化，这一发现可能为 IA 的发病机制提供新的视角。
