Kapoula Z, Yang Q, Vernet M, Bonfils P, Londero A
Laboratoire IRIS, CNRS, FRE 3154, Service d'Ophtalmologie-ORL-Stomatologie, Hôpital Européen Georges Pompidou, 20 rue Leblanc, Paris, France.
Auris Nasus Larynx. 2010 Jun;37(3):314-21. doi: 10.1016/j.anl.2009.10.004. Epub 2009 Nov 17.
Smooth pursuit (SP), optokinetic nystagmus (OKN) and fixation were investigated in five subjects with somatic tinnitus modulated by eye movements, jaw or neck.
Eye movements were recorded with the EyeLink II video system.
(1) Fixation was characterized by high frequency and amplitude of saccade intrusions; (2) SP had low gain particularly in the vertical direction, and it was characterized by high frequency of catch-up saccades with high amplitude, including predictive saccades; (3) OKN also had low gain particularly in the vertical direction. Each subject showed abnormality for more than one type of eye movement, and for specific directions.
The results suggest mild dysfunction of cortical-subcortical and cerebellar structures involved in the control of these eye movements. Particularly deficits for vertical pursuit eye movements and fixation instability in line with cerebellar signs. Further studies of more patients with or without modulated tinnitus are in progress.
对五名患有由眼球运动、下颌或颈部调节的躯体性耳鸣的受试者进行平稳跟踪（SP）、视动性眼震（OKN）和注视研究。
使用EyeLink II视频系统记录眼球运动。
（1）注视的特征是扫视侵入的频率和幅度较高；（2）平稳跟踪的增益较低，尤其是在垂直方向，其特征是具有高幅度的追视扫视频率较高，包括预测性扫视；（3）视动性眼震的增益也较低，尤其是在垂直方向。每个受试者在不止一种眼球运动类型以及特定方向上表现出异常。
结果表明参与这些眼球运动控制的皮质 - 皮质下和小脑结构存在轻度功能障碍。特别是垂直跟踪眼球运动的缺陷和与小脑体征一致的注视不稳定。正在对更多有或没有调节性耳鸣的患者进行进一步研究。
