Misciagna Sandro, Iuvone Laura, Mariotti Paolo, Silveri Maria Caterina
Unit of Neurological Rehabilitation, Fondazione Don Gnocchi, Centro Santa Maria della Pace, Rome, Italy.
Neurocase. 2010 Apr;16(2):119-24. doi: 10.1080/13554790903329158. Epub 2009 Nov 18.
The impairment of phonological short-term memory has been reported in adults with cerebellar lesions. At the same time, a role of the cerebellum in speech production has been hypothesized. Cerebellar malformations have been related to developmental problems and language acquisition in children. We describe a 5-year-old male child with cerebellar vermis hypoplasia who presented a severe linguistic deficit. On language testing, verbal production was almost absent, while comprehension was partially spared. Digit span was markedly reduced. An extensive examination of phonological short-term memory confirmed a deficit at this level. Positron Emission Tomography revealed hypometabolism both in the cerebellum and the supratentorial areas involved in language function. This finding supports the hypothesis that the cerebellum is included in a cerebro-cerebellar network, that underlies the phonological short-term memory, whose integrity is necessary for language acquisition.
据报道，患有小脑病变的成年人存在语音短期记忆障碍。与此同时，有人推测小脑在言语产生中发挥作用。小脑畸形与儿童发育问题和语言习得有关。我们描述了一名患有小脑蚓部发育不全的5岁男童，他存在严重的语言缺陷。在语言测试中，几乎没有言语表达，而理解能力部分保留。数字广度明显降低。对语音短期记忆的广泛检查证实了这一水平存在缺陷。正电子发射断层扫描显示，小脑和参与语言功能的幕上区域均存在代谢减退。这一发现支持了以下假设：小脑包含在一个脑-小脑网络中，该网络是语音短期记忆的基础，其完整性对于语言习得是必要的。
